Space Milkshake (2012)

Four blue collar astronauts who are stuck together on a Sanitation Station after they bring a mysterious device aboard their ship and all life on Earth disappears. Discovering what happened to civilization is only the first of many galactic-level crises the astronauts will have to face as they are about to come under attack by a mutating rubber duck named Gary, who wants to open a portal to his evil dimension and take over the Universe.